The unfolded protein response in virus infections
نویسندگان
چکیده
منابع مشابه
The unfolded protein response in virus infections
Unfolded protein response (UPR) is a cellular homeostatic response to endoplasmic reticulum (ER) stress. Increasing evidence suggests an intimate relationship between virus and UPR. This research topic collated a number of review articles and original research article, in an attempt to highlight how viruses interact with the host UPR in the establishment of acute, chronic and latent infections....
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Where does the UPR function? Between the endoplasmic reticulum (ER) and the nucleus of eukaryotic cells. All secreted proteins and proteins that reside in secretory compartments translocate as nascent peptide chains into the ER, where they may undergo folding, modification and assembly before assuming their functional conformations. The ER maintains a specialized oxidizing environment to aid ch...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2014
ISSN: 1664-302X
DOI: 10.3389/fmicb.2014.00518